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Frequently Asked Questions

“Extraction in Seconds”. Due to the in-tip dispersive nature of DPX dSPE tips, extraction occurs rapidly during simple aspiration and dispense steps. Customers typically find that sample preparation time is significantly reduced when compared to traditional SPE. DPX tips seamlessly integrate onto automated liquid handlers for unparalleled ease-of-use.

DPX offers two different approaches to urine preparation.

  1. The first is a simple filtration of post-hydrolysis urine samples. DPX filtration tips utilizing Tip-on-Tip (ToT) technology provide a simple, fast, and effective way to filter sub-micron particulates/protein/enzyme from urine samples. The online filtration process takes less than two minutes and provides an automated alternative to centrifugation.
  2. The second approach uses dispersive solid-phase extraction (dSPE) tips to offer the cleanest samples for injection. Our in-tip dSPE technology promotes minimal sorbent mass allowing for low volume elution and dilution, thereby circumventing the need for solvent evaporation. Cleaner extracts lead to longer column life, less LC-MS/MS maintenance, fewer repeat injections, and reduced data analysis time.

Whether you are in the early stages of method development with a new application or are seeking to enhance current throughput, DPX products offer a solution! DPX offers a variety of workflow solutions that are compatible with most pipetting systems-manual, semi-automated, and fully automated. Connect with us for more information.

DPX can customize tips in the form of various sorbent types and amounts. DPX is proud to offer confidential product customization, method development, and workflow solutions. Connect with us for more information.

DPX tips are routinely used with whole blood, serum, urine, oral fluid and solid biological specimens in a variety of applications. The DPX technology portfolio combined with various sorbent types and filtration mediums facilitate solutions for the majority of analyte/matrix variations.

We recommend that you first explore the various DPX technologies and methodologies. After isolating the appropriate methodology, the sorbent type/amount or filtration porosity is selected based on the analytes of interest or matrix, respectively.

Since the possibilities are endless, please reach out to one the of DPX scientists for product/method recommendations. You can also explore our resources section for previously established methods.

Certainly! DPX Technologies has been recognized for its outstanding on-site customer support. We provide confidential and customized technical assistance with method development and/or validation as you incorporate our products into your workflow. Contact us to discuss this program.

Yes! It is very important to us that customers validate our products in their laboratories. DPX tip technology continues to be highlighted in a number of peer-reviewed publications and presentations. Click here for a list of citations.

Absolutely! We have partnered with a number of leading manufacturers in order to provide customized high-throughput solutions. For example, we have developed technical applications specific to urine and oral fluid using Hamilton and Tecan liquid handling workstations. Whether you are currently using laboratory automation or are seeking to incorporate it into your sample preparation process, DPX Technologies offers seamless integration with a number of liquid handling platforms. Connect with us to learn more.

Yes! DPX tips are used in academia, start-up labs and those without automated liquid handlers. Our tips are designed to work with many hand held pipettes, semi-automated platforms and our own pneumatic extractor. Contact us for more information.