NEW!   DPX introduces Tip-on-Tip Technology.Learn More

MSACL 2019

MSACL 2019

DPX Technologies at MSACL

We are excited to showcase our new Tip-on-Tip Technology at the MSACL conference this year. We will be presenting a poster with Hamilton Robotics and Standford Health Care.

Poster Title: Automated Method for High-Throughput LC-MS/MS Quantitation of Testosterone from Serum: Validation and Interlaboratory Comparison

Abstract: A novel automated method for the quantitation of testosterone in serum was developed using DPX Low Porosity Filtration Tips (LPFT) on a Hamilton MICROLAB® NIMBUS96 system with liquid chromatography tandem mass spectrometry (LC-MS/MS). The tip-based method uses a quick (< 2 min) and effective, DPX patent-pending, Tip-on-Tip technology that provides an automated alternative to centrifugation and filtration. Calibrations for testosterone were linear over a range of 2.0 ng/dL to 1000 ng/dL with a correlation coefficient 0.9997. A blind study with a corresponding laboratory based on 55 positive patient samples produced an R2 value of 0.9808 for quantitative results.

Visit Poster #13 at MSACL!

About Tip-on-Tip Technology

Tip-on-Tip (ToT) is a patent pending technology that was designed to promote the simplification and automation of complex sample preparation. The ToT technology has two main methodologies: ToT Filtration and ToT SPE. This technology provides a fast, automated INTip solution for a variety of applications.

ToT Filtration
ToT Filtration combines a conductive wide bore top tip with a bottom Filtration tip to provide an automated alternative to traditional filtration/centrifugation. This methodology is ideal for high-throughput online protein precipitation and filtration, beta-glucuronidase removal, or any other particulate removal. Filtration tips can be ordered in low porosity, dual phase or single phase.

Advantages:

  • Automated solution
  • Variety of applications
  • No positive pressure/vacuum manifold
  • High throughput
  • Low cost

ToT SPE
ToT SPE Technology provides a fast, automated INTip solution for a variety of applications including immunoaffinity. ToT SPE is ideal for applications that require specific incubation conditions between sorbent and sample solution.

Advantages:

  • Automated solution
  • Variety of applications
  • High throughput
  • Customizable Sorbent

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