Dispersive Pipette XTRaction technology introduces the benefits of solid phase extraction into a revolutionary, easy-to-use pipette tip. This device is unique from fixed-bed resin formats because sorbent material is loosely contained within a tip.

XTRactions are fast! Depending on the application, our customers typically find that extraction time is significantly reduced when compared to traditional SPE. XTR tips are designed to work seamlessly on robotic liquid handlers, unlike conventional SPE.

The disperser helps to perturb the sample solution and loose sorbent during aspirate and dispense steps. This mixing provides a highly efficient interaction of the sorbent and sample solution resulting in ideal analyte recoveries and reduced matrix effects. You can seamlessly integrate XTR tips with any workflow or method.

INTip SPE

XTR - Universal style 1 mL tip

Barrier

Disperser

Loose Sorbent

Frit

• XTR Tip Anatomy

• Cleanup Workflow

• Bind-Wash-Elute Workflow

• XTR on Hamilton Robotics

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Dispersive
XTRaction
SPE
Cartridge
96-well
plate
Customization
High efficiency
Low sample
volumes
Reduced solvent
volumes
Scalable
Process 1 - 96
Automation
No hardware
required

Aspirate Sample

Easy Sample Cleanup

Mix sample via aspirate and dispense steps

Interferents Bind to Sorbent

Dispense Analyte
of Interest

  • No vacuum manifold
  • Unparalleled ease of use
  • Low cost, automated solution
  • Custom method development

Bind - Wash - Elute

Condition

Bind

Disperser forces turbulent mixing of loose sorbent

Interferents Wash Off

Elute Analyte of Interest

Analyte Binds
to Sorbent

Wash

Elute

  • Rapid extraction times
  • Higher analyte recoveries
  • Sorbent chemistry customization