• XTR Tip Anatomy

• Cleanup Workflow

• Bind-Wash-Elute Workflow

• Matrices

INTip Solid Phase Extraction - powered by patented Dispersive Pipette XTRaction Technology

The disperser in XTR tips perturbs the sample solution and loose sorbent during aspirate and dispense steps. This mixing provides a highly efficient interaction of the sorbent with the analyte of interest resulting in ideal analyte recoveries.

You can seamlessly integrate XTR tips with any workflow or method. Pipette tips are available in manual, semi-automated or fully automated formats.

Click the links to sort the slider.

300 μL XTR Tips on a Hamilton STAR 8 channel head

Aspirate Sample

Easy Sample Cleanup

Mix Sample

Interferents Bind to Sorbent

Dispense Analyte
of Interest

sample preparation for blood for mass spectrometry analysisSample preparation for hair samples for mass spectrometry analysissample preparation for meconium for mass spectrometry analysissample preparation for oral fluid for mass spectrometry analysissample preparation for urine for mass spectrometry analysis

Urine

Blood/Serum

Meconium

Oral Fluid

Plant Material

Hair

Food Extract

Tissue

Matrices

Dispersive Pipette XTRaction enables INTip solid phase extraction for easy sample preparation. The disperser helps to perturb the sample solution and loose sorbent during aspirate and dispense steps. This mixing provides a highly efficient interaction of the sorbent with the analyte of interest resulting in ideal analyte recoveries.

You can seamlessly integrate XTR tips with any workflow or method. Pipette tips are available in manual, semi-automated or fully automated formats.

• XTR Tip Anatomy

• Cleanup Workflow

• Bind-Wash-Elute Workflow

• Matrices

300 μL XTR Tips on a Hamilton STAR 8 channel head

Click the links to navigate the slider.

Aspirate Sample

Easy Sample Cleanup

Mix Sample

Interferents Bind to Sorbent

Dispense Analyte
of Interest

sample preparation for blood for mass spectrometry analysisSample preparation for hair samples for mass spectrometry analysissample preparation for meconium for mass spectrometry analysissample preparation for oral fluid for mass spectrometry analysissample preparation for urine for mass spectrometry analysis

Urine

Blood/Serum

Meconium

Oral Fluid

Plant Material

Hair

Food Extract

Tissue

Matrices

INTip Filtration - powered by patent-pending Tip-on-Tip (ToT) Technology

A top tip aspirates sample solution, fits into the Filtration tip, and dispenses through the Filtration tip providing a clean, particulate-free solution. Filtration tips are available in a variety of porosities. ToT has three main methodologies: ToT Filtration, ToT Cleanup and ToT SPE.

Click the links to sort the slider.

• SPE Method

• Protein Precipitation Method

• Simple Filtration Workflow

• Anatomy

• Cleanup Workflow

Single Phase Filtration Tips with a disperser for ToT SPE Methods shown here

ToT Anatomy

Top- Wide Bore Conductive Tip

Filtration Tip

Gasket - provides air tight hold

Filter Options
Dual Phase - shown here
Low Porosity
Single Phase

Aspirate Dirty
Sample

Simple Filtration Workflow

Tip-on-Tip (ToT)

Dispense Clean
Sample

Aspirate Sample

Cleanup Workflow - Addition of Sorbent for Cleanup

Tip-on-Tip (ToT)

Analyze

Interferents Bind to Sorbent

Dispense Analyte
of Interest

• Overview

• Anatomy

• Workflow

INTip Size Exclusion Chromatography - powered by patent-pending INTip Swelling

Our size exclusion chromatography product line can be used for desalting and buffer exchange: a group separation method where small molecules (such as salts) are separated from a group of larger molecules (such as proteins.) Samples can be quickly prepared for other downstream chromatography techniques and assays. Our unique INTip swelling method, for the column packing, prepares the gel resin bed for sample loading in less than 20 minutes.

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Frit

SEC Anatomy

Dry resin bed
Resin available in custom amounts and in varying molecular weight cutoffs

SEC Tip - containing 180 mg of dry resin

INTip Swelling- Automated column packing

Swollen resin bed ~ 4.5 cm length for 200 µL sample volume

• Overview

• Anatomy

• Workflow

Click the links for to sort the slider

INTip Filtration utilizes a patent-pending Tip-on-Tip technology designed to promote the simplification and automation of complex sample preparation for a variety of applications. ToT combines a conductive wide bore top tip with a bottom Filtration tip to provide an automated alternative to traditional filtration/centrifugation. ToT has three main methodologies: ToT Filtration, ToT Cleanup, and ToT SPE

• SPE Method

• Filtration for Protein Precipitation

• Simple Filtration Method

• Cleanup Method

Single Phase Filtration Tips with a disperser for ToT SPE Methods shown here

Click the links to navigate the slider.

Aspirate Dirty
Sample

ToT Simple Filtration

Tip-on-Tip (ToT)

Dispense Clean
Sample

Aspirate Sample

ToT Filtration Cleanup - Addition of Sorbent for Cleanup

Tip-on-Tip (ToT)

Analyze

Interferents Bind to Sorbent

Dispense Analyte
of Interest

XTR

ToT

SEC