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DPX Technologies Announces a New INTip Solution for Micro-elution

Columbia, SC – DPX Technologies announces a new INTip solution that utilizes a proprietary design for micro-elution dispersive solid phase extraction. DPX INTip solutions are designed to simplify sample preparation methods, and the μElution dSPE tip provides an automated solution for optimal sensitivity. “The μElution dSPE tips were developed as an addition to the dSPE product line, that gives our customers the ability to reduce elution volumes and increase sensitivity for downstream analysis,” said William E. Brewer, Ph.D., Founder and [...]

DPX Technologies Announces a New INTip Solution Utilizing Tip-on-Tip Technology

Columbia, SC – DPX Technologies announces a new INTip solution that utilizes a patent pending Tip-on-Tip (ToT) technology. ToT technology was a natural progression of the DPX INTip product line designed to promote the simplification and automation of complex sample preparation. The ToT technology has two main methodologies: ToT Filtration and ToT SPE. This technology provides a fast, automated INTip solution for a variety of applications. “The beauty of this technology is in the versatility. We partner with our customers to solve bottlenecks they are [...]

Novel Protein Precipitation Method for Whole Blood Using Automated Tip-on-Tip Technology

Purpose Introduce innovative automated multi-purpose INTip filtration technologyDemonstrate the feasibility of a novel and rapid protein precipitation method, often referred to as “protein crash”.This method can be extended to many areas of science, including drug discovery, metabolomics, and clinical trial studies.This automated procedure could be applied to applications such as gelatin removal from drug formulations or processing cell lysates. All sample preparation was performed on a Hamilton NIMBUS96 platform.  This study shows that efficient protein precipitation using an automated liquid handler [...]

Automated Extraction of Catecholamines and Metanephrines in Urine

Introduction: The catecholamines are bioamines that play an integral role as neurotransmitters in the central and peripheral nervous system. Screening for catecholamines and their O-methylated metabolites is a widely accepted approach for diagnosis of catecholamine-secreting tumors. Generally, these tumors are benign, but the potent effects on the cardiovascular system caused by excess catecholamines can have potentially fatal outcomes. Correct, timely diagnosis is crucial. Unlike plasma, it is recommended that both metanephrines and catecholamines be measured in urine. Urine analysis is [...]

MSACL 2019

DPX Technologies at MSACL We are excited to showcase our new Tip-on-Tip Technology at the MSACL conference this year. We will be presenting a poster with Hamilton Robotics and Standford Health Care. Poster Title: Automated Method for High-Throughput LC-MS/MS Quantitation of Testosterone from Serum: Validation and Interlaboratory Comparison Abstract: A novel automated method for the quantitation of testosterone in serum was developed using DPX Low Porosity Filtration Tips (LPFT) on a Hamilton MICROLAB® NIMBUS96 system with liquid chromatography tandem mass spectrometry (LC-MS/MS). [...]

Hamilton Robotics and DPX Technologies Announce INTip Chemistry, the Next Phase in Sample Preparation

The jointly developed INTip Chemistry enables scientists to fully automate sample preparation at a fraction of the time, cost and effort of traditional SPE systems. RENO, Nev. (July 28, 2016) — Hamilton Robotics and DPX Technologies, LLC (DPX®) have announced a collaboration leveraging their expertise in the fields of automated liquid handling and dispersive solid phase extraction to develop high-throughput solutions for clinical, forensic and food safety laboratories. The revolutionary INTip Chemistry merges the precision of Hamilton’s patented CO-RE® tip [...]