XTR: INTipTM Solid Phase Extraction (SPE)

INTip SPE utilizes a patented technology known as Dispersive Pipette XTRaction. This device is unique from all other SPE devices because sorbent is loosely contained within a pipette tip.

High Quality Sorbents

DPX offers sorbent chemistries in a range of phases to capture unique selectivity for a diverse spectrum of analytes. XTR tips are manufactured to order per custom specifications. They can hold 1 – 100 mg of sorbent depending on the tip format.

Supel™ Swift HLB SPE from Millipore Sigma is a proprietary and patent pending copolymer having both hydrophilic and lipophilic functional groups. The sorbent’s dual polarity nature makes it ideal for extracting a broad range of compounds from aqueous matrices, and is an appropriate choice in applications for food & environmental samples as well as biological samples such as urine, serum and plasma. The hydrophilic and lipophilic balance (HLB) property of the polymer material enables the retention of a wide range of compounds having a wide range of polarities and Log P values.

Our reversed phase sorbent is a styrene divinylbenzene polymer with an average particle size of 75 μm. It is ideal for nonpolar and slightly polar compounds.

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Our weak anion exchange (WAX) sorbent has a secondary amine phase with a styrene divinyl benzene backbone for the binding of strong acids, such as sulphates. WAX sorbents are offered in 10-20 μm and 55-65 μm particle size ranges.

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Our weak cation exchange (WCX) sorbent has a carboxylic acid stationary phase with a styrene divinyl benzene backbone for the binding of strong bases such as quaternary amines. WCX sorbent is offered in a 30-70 μm particle size range.

Our strong cation exchange (SCX) sorbent has a sulfonated stationary phase with a styrene divinyl benzene backbone for the binding of basic compounds. SCX sorbents are offered in 10-20 μm, 25-35 μm and 55-65 μm particle size ranges.

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Our strong anion exchange (SAX) sorbent has a quaternary amine phase with a styrene divinyl benzene backbone for the binding of acidic compounds. SAX sorbent is offered in a 55-65 μm particle size range.

Our silica sorbent is amenable to extraction via hydrogen bonding. It is available in a 40-60 μm particle size range.

Our C18 sorbent has a silica gel backbone. It is endcapped, with a carbon load of 18-22%, and 40-60 μm particle size range.

DPX is proud to offer HybridSPE® (a Supelco/Millipore Sigma product) sorbent. It is a proprietary zirconia coated silica that selectively removes phospholipids from biological samples.

  • Unique chemistry for excellent recovery of both hydrophobic and hydrophilic analytes

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Our mixed mode products are completely customized by choosing any of the above chemistries to combine in one tip. Each sorbent’s mass can also be customized for optimal extraction characteristics for any analyte/matrix combination.

Ex. WAX/RP, WAX/SCX

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Combine Dispersive Pipette XTRaction and SALLE (Salt Assisted Liquid-Liquid Extraction) for a novel cleanup mechanism. XTR tips can house sorbents like WAX or RP for cleanup and the salt (S) necessary for SALLE. This methodology is ideal for applications that require acetonitrile for protein precipitation and are focused on hydrophobic analytes.

Ex. WAX-S, RP-S

Aspirate and dispense steps mix sample solution and loose sorbent material. Added salt (S) assists in phase separation during extraction.

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Learn more about WAX-S Methods

Automation Compatibility

XTR tips come in a variety of formats to be used on the most common automated liquid handlers from the companies below. If your automation vendor is not listed here, please contact us to discuss custom options.

Compatibility:

  • Microlab NIMBUS, STAR, and VANTAGE systems – all sizes and configurations

Pipette Tip Sizes:

  • 1mL, 300 μL, and  300 μL µXTR – (micro-elution tip)

Notes:

XTR tips for Hamilton utilize the CO-RE® Technology. Custom method development is available.

Compatibility:

  • Evolve, Voyager, VIAFLO ASSIST, and VIAFLO96 systems

Pipette Tip Sizes:

  • 1250 μL, 300 µL, and 300 μL µXTR – (micro-elution tip)

Pipette Tip Size:

  • 1mL, 300 μL, and 300 μL µXTR – (micro-elution tip)

Notes:

If you have a Gerstel MPS system and want to try XTR tips please contact Gerstel.

Pipette Tip Size:

  • 1 mL and 200 µL

Pipette Tips for Rainin LTS

  • 1 mL and 250 µL

Pipette Tip Size:

  • 1 mL tips compatible with select Opentrons configuration. Contact us for more information.

Pipette Tip Size:

  • 1 mL

Pipette Tip Size:

  • 1 mL

COMING SOON!

Pipette Tip Sizes:

  • 1 mL

Notes:

These tips are epT.I.P.S.® for epMotion

Pipette Tip Sizes:

  • 1 mL – Fits single and multichannel pipettes and the DPX 1 mL pneumatic extractor.
  • 5 mL – Comes with a syringe for manual use. This is the largest tip offered.

Notes:

This tip fits most single or multi-channel pipettors.

Notes:

DPX offers a 1 mL Pneumatic Extractor. This devices drives syringes to create positive and negative pressure to aspirate and dispense solutions in and out of universal style tips. The Pneumatic Extractor can process 24 – 96 samples at one time.

Request a Sample

Evaluate XTR tips with the chemistry you need for solid phase extraction. If you know exactly what options you want, fill out the product ordering form and specify your request.