SLAS Solution Spotlight: Bead-free DNA Cleanup and Size Selection
Bead-Free Automated Cleanup and Size-Selection with DPX INTip Solutions for NGS Library Preparation
NiXTips® from DPX Technologies offer a streamlined alternative to magnetic bead-based methods by integrating proprietary silica media directly into automation compatible pipette tips for nucleic acid extraction, cleanup, and size selection suitable for NGS library preparation. This approach enables a simple bind–wash–elute workflow performed within the NiXTip without beads, magnets, or additional hardware. Unlike magnetic beads which require careful resuspension, magnet-based pelleting, and cold storage, NiXTips are handled like standard consumables, making them ideal for high-throughput automation. NiXTips eliminate issues such as bead carryover and laborious bead-based method optimization while reducing overall pipette tip waste. Additionally, NiXTips support rapid processing in 96 or 384 formats compatible with many automated liquid handling platforms.
Learn More abot NiXTips
NiXTips are functionalized pipette tips containing a proprietary microporous silica media. NiXtips can be used for DNA extraction from biological samples like whole blood, saliva or cell culture, and for DNA purification for PCR cleanup or size selection.
