Improve sample preparation for biological matrices

INTip Solid Phase Extraction utilizes a patented technology known as Dispersive Pipette XTRaction. This device is unique from all other SPE devices because sorbent is loosely contained within a pipette tip. The disperser in XTR tips helps to perturb the sample solution and loose sorbent during aspirate and dispense steps. This mixing provides a highly efficient interaction of the sorbent with the analyte of interest resulting in ideal analyte recoveries.

Dispersive XTRaction

  • Customization

  • High efficiency

  • Low sample volumes

  • Reduced solvent volumes

  • Scalable
    Process 1- 96 samples

  • Automation

  • No hardware required

SPE Cartridge

Sample, wash and elution solvents flow through the sorbent in one direction. SPE cartridges are not automation compatible.

SPE 96- well plate

Sample, wash and elution solvents flow through the sorbent in one direction. 96-well plates do offer automation, but additional hardware like a vacuum or positive pressure manifold is required.

Traditional solid phase extraction products are packed with a fixed-bed, which only allows a solution to flow through in one direction. Additional hardware like a positive pressure manifold or vacuum block is required. Dispersive Pipette XTRaction is not dependent on flow rates since the solution is mixed with the chemistry. This technology has been featured in a number of publications that show-case high recoveries and reduced matrix effects for various applications. Extraction takes seconds and entire workflows can be fully automated. Moreover, Dispersive Pipette XTRaction is very cost-effective because a significant amount of sorbent and solvents can be saved.

  • Pipette tips are easy-to-use and easy-to-automate!
  • Reduce failure rates
  • Robust sample preparation
  • High recoveries
  • Sorbent customization
  • Optimized high-throughput workflows

How to Order:

Choose the tip style, size, chemistry and amount in your tip.

For more information about each sorbent chemistry offered visit our product page.

Contact us and one of our application scientists will send you a recommended protocol. We also offer confidential on-site method development.

XTR Resources:

Generic Protocols for Common Extraction Methods

We put together a series of videos on how to use XTR tips for common extraction methods. The series includes:

  2. Comprehensive Extraction of Drugs and Metabolites from Urine
  3. Rapid Cleanup
  4. DPX + SALLE

Use the guide to learn more about which DPX product can be used with each biological sample matrix. Applications are organized by sample matrix including:

  • Urine
  • Blood
  • Oral fluid
  • Hair
  • Meconium
  • Tissue
  • Cannabis

Our pipette tips are compatible with most automated liquid handlers. Seamless integration onto ALH systems promotes reduced hands-on-time, increased reproducibility and maximum throughput.

  • This field is for validation purposes and should be left unchanged.