Various extraction methods for drugs of abuse in urine have proven to be successful, including the use of HLB (hydrophilic–lipophilic balance) resin in traditional solid phase extraction. The HLB sorbent is extremely versatile in analyte binding because of the co-polymer phase containing both hydrophilic and lipophilic functional groups. In this poster we demonstrate a non-evaporative and highly sensitive extraction method for drugs of abuse in urine; the method gives a total of 10x dilution factor. With this new approach, µXTR (micro-elution XTRaction) tips containing 3 mg of Supel™ Swift HLB is utilized to extract 42 compounds across a large range of polarities. The method uses 50 µL of urine for minimal sample volume and 96 samples can be extracted in 15 minutes.
You can learn more about µXTR tips on our XTR product page. Stay tuned for the full release of this poster following the SOFT conference. Want to make sure you don’t miss any updates? Sign up to receive our newsletter via the form on the side of this blog.