Journal Articles and Applications using Alternative Matrices in Forensic Toxicology

Dr. William Brewer, founder and CEO of DPX Technologies, recently participated in an expert led panel discussion on alternative matrices in forensic toxicology. His portion of the discussion focused on oral fluid extraction for drugs of abuse testing. When working with oral fluid, sample preparation is required in order to minimize matrix effects due to both saliva and collection device buffer in oral fluid samples prior to LC-MS/MS analysis. Multi-step SPE column preparation and multiple extractions add to turn-around-time creating a bottle-neck in sample throughput for laboratories. To address these SPE limitations we have developed fast methods for comprehensive analysis of oral fluid samples using Dispersive Pipette XTRaction technology. We have an article that outlines our method development approach for oral fluid extraction.

Hair, Nails and Meconium – Journal Articles using XTR tips for solid phase extraction

The discussion on alternative matrices sparked further questions around sample preparation for hair, nails and meconium. We searched the database of articles in the Journal of Analytical Toxicology to find references that use XTR tips for solid phase extraction with these other alternative matrices.

This article mentions the use of Disposable Pipette Extraction which has rebranded to be known as Dispersive Pipette XTRaction. Read the article on the rebrand. 

Looking for solid phase extraction products?

DPX Technologies manufactures sample preparation products and develops methods for a diverse range of applications. The INTip solid phase extraction product line includes XTR tips and µXTR tips offered on the largest range of pipetting platforms.

DPX offers sorbents chemistries in a range of phases to capture unique selectivity for a diverse spectrum of analytes. XTR tips can hold 1 – 100 mg of sorbent depending on the tip format.

FORENSIC APPLICATIONS USING DPX PRODUCTS